ASPECTOS GERAIS DA QUÍMICA DOS DITIOCARBAMATOS E DE SEUS COMPLEXOS METÁLICOS E INTERAÇÕES DESSAS ESPÉCIES QUÍMICAS COM IMPORTANTES ENZIMAS – UMA BREVE REVISÃO

GENERAL ASPECTS OF THE CHEMISTRY DITHIOCARBAMATES, THEIR METALLIC COMPLEXES AND INTERACTIONS WITH IMPORTANTE ENZYMES – A BRIEF REVISION. Dithiocarbamates (DTCs) comprise a series of compounds included in the class 1,1`dithiolates. The application these organic molecules coordination chemistry some metals is well explored last decades, along with their potential applications medicinal chemistry. In view our expertise this field, syntheses new DTCS, towards various metallic cations and biocide activities, we summarize manuscript outcomes investigations registered literature, involving interactions DTCs or complexes key enzymes such as carbonic anhydrases, superoxide dismutase, urease, tyrosinase, glutathione, caspases dehydrogenases. It provided brief introduction DTCs, electrochemistry, kinetics formation, solubility stability solvation. next topics results experiments concerning inhibition cited effected by complexes. final remarks conclusion are at end manuscript.